Reaction: Northiaden to 1 product

Reaction
Northiaden
DBMET01516
    Northiaden S-oxide
    DBMET01520
    Reaction type
    S-oxidation
    Direction
    Major circulating metabolite?
    Yes
    Spontaneous?
    No
    Activity
    unknown
    References
    1. Maguire KP, Burrows GD, Norman TR, Scoggins BA: Metabolism and pharmacokinetics of dothiepin. Br J Clin Pharmacol. 1981 Sep;12(3):405-9. [Article]
    2. Fulton A, Norman TR, Cheng H, Burrows GD: Assessment of the antidepressant activity of dothiepin and its metabolites by preclinical tests. J Affect Disord. 1982 Sep;4(3):261-9. [Article]
    Comments
    Not Available
    Enzymes
    Not Available