Reaction: Tegaserod to 1 product

Reaction
Tegaserod
DB01079
    5-methoxyindole-3-carboxylic acid
    DBMET02368
    Reaction type
    glucuronidation; hydrolysis; oxidation
    Direction
    Major circulating metabolite?
    Yes
    Spontaneous?
    No
    Activity
    inactive
    References
    1. Vickers AE, Zollinger M, Dannecker R, Tynes R, Heitz F, Fischer V: In vitro metabolism of tegaserod in human liver and intestine: assessment of drug interactions. Drug Metab Dispos. 2001 Oct;29(10):1269-76. [Article]
    Comments
    The reaction types occur in the order of i) hydrolysis, ii) oxidation, and then iii) glucuronidation.
    Enzymes
    Not Available