Reaction: Apixaban to 1 product

Reaction
Apixaban
DB06605
    Apixaban M2 metabolite
    DBMET02426
    Reaction type
    O-demethylation
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    inactive
    References
    1. Raghavan N, Frost CE, Yu Z, He K, Zhang H, Humphreys WG, Pinto D, Chen S, Bonacorsi S, Wong PC, Zhang D: Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab Dispos. 2009 Jan;37(1):74-81. doi: 10.1124/dmd.108.023143. Epub 2008 Oct 2. [Article]
    Comments
    Not Available
    Enzymes
    Not Available