Reaction: Methimazole to 1 product

Reaction
Reaction type
ketone formation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Skellern GG, Knight BI, Low CK, Alexander WD, McLarty DG, Kalk WJ: The pharmacokinetics of methimazole after oral administration of carbimazole and methimazole, in hyperthyroid patients. Br J Clin Pharmacol. 1980 Feb;9(2):137-43. doi: 10.1111/j.1365-2125.1980.tb05823.x. [Article]
Comments
Antithyroid activity of this metabolite has been suggested but not confirmed.
Enzymes
Not Available