Reaction: Methimazole to 1 product
- Reaction
- Reaction type
- ketone formation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Skellern GG, Knight BI, Low CK, Alexander WD, McLarty DG, Kalk WJ: The pharmacokinetics of methimazole after oral administration of carbimazole and methimazole, in hyperthyroid patients. Br J Clin Pharmacol. 1980 Feb;9(2):137-43. doi: 10.1111/j.1365-2125.1980.tb05823.x. [Article]
- Comments
- Antithyroid activity of this metabolite has been suggested but not confirmed.
- Enzymes
- Not Available