Reaction: Fludrocortisone to 1 product

Reaction
Fludrocortisone
DB00687
    20β-dihydrofluorocortisol
    DBMET02845
    Reaction type
    reduction
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    unknown
    References
    1. Abel SM, Back DJ, Maggs JL, Park BK: Cortisol metabolism by human liver in vitro--IV. Metabolism of 9 alpha-fluorocortisol by human liver microsomes and cytosol. J Steroid Biochem Mol Biol. 1993 Dec;46(6):833-9. doi: 10.1016/0960-0760(93)90326-r. [Article]
    Comments
    The specific enzyme responsible for this conversion is unclear. This reaction has been observed in both liver microsomes and cytosol.
    Enzymes
    Not Available