Reaction: Fludrocortisone to 1 product
6-hydroxylationMetabolism of Fludrocortisone
Fludrocortisone is converted to 6β-hydroxyfluorocortisol.
- Reaction
- Direction
- Comments
- The specific enzyme responsible for this conversion is unclear, however studies looking at the in vitro metabolism of fludrocortisone have observed this metabolite only after incubation in liver microsome (with none generated following incubation in liver cytosol).
What you can answer from here — as of October 15, 2019
Which metabolites of Fludrocortisone are active, and how do they change its interactions?
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