Reaction: Norethisterone to 1 product

Reaction
Norethisterone
DB00717
5α-dihydronorethisterone
DBMET02891
Reaction type
reduction
Direction
Not Available
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Schoonen WG, Deckers GH, de Gooijer ME, de Ries R, Kloosterboer HJ: Hormonal properties of norethisterone, 7alpha-methyl-norethisterone and their derivatives. J Steroid Biochem Mol Biol. 2000 Nov 15;74(4):213-22. doi: 10.1016/s0960-0760(00)00125-4. [Article]
  2. Walker CJ, Cowan DA, James VH, Lau JC, Kicman AT: Doping in sport: 3. Metabolic conversion of oral norethisterone to urinary 19-norandrosterone. Steroids. 2009 Mar;74(3):341-9. doi: 10.1016/j.steroids.2008.11.008. Epub 2008 Nov 19. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
3-oxo-5-alpha-steroid 4-dehydrogenaseNot AvailableNot Availableimplied