Reaction: Lopinavir to 1 product

Reaction
Lopinavir
DB01601
    Lopinavir M2 metabolite
    DBMET03069
    Reaction type
    oxidation
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    unknown
    References
    1. Kumar GN, Jayanti V, Lee RD, Whittern DN, Uchic J, Thomas S, Johnson P, Grabowski B, Sham H, Betebenner D, Kempf DJ, Denissen JF: In vitro metabolism of the HIV-1 protease inhibitor ABT-378: species comparison and metabolite identification. Drug Metab Dispos. 1999 Jan;27(1):86-91. [Article]
    Comments
    Not Available
    Enzymes
    Not Available