Reaction: M8 (N-desmethyl selumetinib) to 1 product

eliminationMetabolism of Selumetinib

M8 (N-desmethyl selumetinib) is converted to M12 (Primary amide, N-demethylated selumetinib metabolite).

Reaction
M8 (N-desmethyl selumetinib)
DBMET03102
    M12 (Primary amide, N-demethylated selumetinib metabolite)
    DBMET03101
    Direction

    Which metabolites of M8 (N-desmethyl selumetinib) are active, and how do they change its interactions?

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