Reaction: M8 (N-desmethyl selumetinib) to 1 product

M8 (N-desmethyl selumetinib) is converted to M11 (N-demethylated carboxylic acid selumetinib metabolite).

Direction

Which metabolites of M8 (N-desmethyl selumetinib) are active, and how do they change its interactions?

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