Reaction: M12 (Primary amide, N-demethylated selumetinib metabolite) to 1 product

oxidationMetabolism of Selumetinib

M12 (Primary amide, N-demethylated selumetinib metabolite) is converted to M13 (Primary amide, N-demethylated, mono-oxidized selumetinib metabolite).

Reaction
M12 (Primary amide, N-demethylated selumetinib metabolite)
DBMET03101
    M13 (Primary amide, N-demethylated, mono-oxidized selumetinib metabolite)
    DBMET03111
    Direction

    Which metabolites of M12 (Primary amide, N-demethylated selumetinib metabolite) are active, and how do they change its interactions?

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