Reaction: Sacituzumab govitecan to 1 product
Sacituzumab govitecan is converted to SN-38.
- Reaction
- Direction
- Activity
- active
- Comments
- Cleavage is thought to be mediated by pH changes, such as those encountered in cell lysosomes and/or the tumour microenvironment.
What you can answer from here — as of April 24, 2020
Which metabolites of Sacituzumab govitecan are active, and how do they change its interactions?
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