Reaction: Furosemide to 1 product
- Reaction
- Reaction type
- N-dealkylation
- Direction
- Not Available
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Perez J, Sitar DS, Ogilvie RI: Biotransformation of furosemide in patients with acute pulmonary edema. Drug Metab Dispos. 1979 Nov-Dec;7(6):383-7. [Article]
- Williams DP, Antoine DJ, Butler PJ, Jones R, Randle L, Payne A, Howard M, Gardner I, Blagg J, Park BK: The metabolism and toxicity of furosemide in the Wistar rat and CD-1 mouse: a chemical and biochemical definition of the toxicophore. J Pharmacol Exp Ther. 2007 Sep;322(3):1208-20. doi: 10.1124/jpet.107.125302. Epub 2007 Jun 7. [Article]
- Comments
- Not Available
- Enzymes
- Not Available