Reaction: Furosemide to 1 product

Reaction
Reaction type
N-dealkylation
Direction
Not Available
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Perez J, Sitar DS, Ogilvie RI: Biotransformation of furosemide in patients with acute pulmonary edema. Drug Metab Dispos. 1979 Nov-Dec;7(6):383-7. [Article]
  2. Williams DP, Antoine DJ, Butler PJ, Jones R, Randle L, Payne A, Howard M, Gardner I, Blagg J, Park BK: The metabolism and toxicity of furosemide in the Wistar rat and CD-1 mouse: a chemical and biochemical definition of the toxicophore. J Pharmacol Exp Ther. 2007 Sep;322(3):1208-20. doi: 10.1124/jpet.107.125302. Epub 2007 Jun 7. [Article]
Comments
Not Available
Enzymes
Not Available