Reaction: Ivosidenib to 1 product

Reaction
Ivosidenib
DB14568
    Ivosidenib M39 metabolite
    DBMET03503
    Reaction type
    hydrolysis
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    inactive
    References
    1. Prakash C, Fan B, Altaf S, Agresta S, Liu H, Yang H: Pharmacokinetics, absorption, metabolism, and excretion of [(14)C]ivosidenib (AG-120) in healthy male subjects. Cancer Chemother Pharmacol. 2019 May;83(5):837-848. doi: 10.1007/s00280-019-03793-7. Epub 2019 Feb 13. [Article]
    2. FDA Approved Drug Products: TIBSOVO (ivosidenib) tablets, for oral use [Link]
    Comments
    Not Available
    Enzymes
    Not Available