Reaction: Leniolisib to 1 product

Reaction
Leniolisib
DB16217
    Leniolisib M1 metabolite
    DBMET03657
    Reaction type
    O-demethylation
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    unknown
    References
    1. Pearson D, Garnier M, Luneau A, James AD, Walles M: (19)F-NMR-based determination of the absorption, metabolism and excretion of the oral phosphatidylinositol-3-kinase (PI3K) delta inhibitor leniolisib (CDZ173) in healthy volunteers. Xenobiotica. 2019 Aug;49(8):953-960. doi: 10.1080/00498254.2018.1523488. Epub 2018 Nov 29. [Article]
    Comments
    Not Available
    Enzymes
    Not Available