Reaction: Tapentadol to 1 product
- Reaction
- Reaction type
- sulfonation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- inactive
- References
- Barbosa J, Faria J, Queiros O, Moreira R, Carvalho F, Dinis-Oliveira RJ: Comparative metabolism of tramadol and tapentadol: a toxicological perspective. Drug Metab Rev. 2016 Nov;48(4):577-592. doi: 10.1080/03602532.2016.1229788. Epub 2016 Sep 15. [Article]
- FDA Approved Drug Products: NUCYNTA (tapentadol) tablets for oral use C-II Initial U.S. (July 2023) [Link]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Sulfotransferase Not Available Not Available implied