Chlorpromazine hydrochlorideProduct ingredient for Chlorpromazine

Name
Chlorpromazine hydrochloride
Drug Entry
Chlorpromazine

The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.

Accession Number
DBSALT000026
Structure
Synonyms
Chlorpromazine HCl
UNII
9WP59609J6
CAS Number
69-09-0
Weight
Average: 355.325
Monoisotopic: 354.072424754
Chemical Formula
C17H20Cl2N2S
InChI Key
FBSMERQALIEGJT-UHFFFAOYSA-N
InChI
InChI=1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
IUPAC Name
[3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine hydrochloride
SMILES
Cl.CN(C)CCCN1C2=CC=CC=C2SC2=C1C=C(Cl)C=C2
KEGG Compound
C07952
PubChem Compound
6240
ChemSpider
6004
ChEBI
3649
ChEMBL
CHEMBL1713
Wikipedia
Chlorpromazine
Predicted Properties
PropertyValueSource
Water Solubility0.00417 mg/mLALOGPS
logP5.18ALOGPS
logP4.54Chemaxon
logS-4.9ALOGPS
pKa (Strongest Basic)9.2Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area6.48 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity93.76 m3·mol-1Chemaxon
Polarizability35.42 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon