Degarelix acetate hydrateProduct ingredient for Degarelix

Name
Degarelix acetate hydrate
Drug Entry
Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in testosterone is important in treating men with advanced prostate cancer. Chemically, it is a synthetic linear decapeptide amide with seven unnatural amino acids, five of which are D-amino acids. FDA approved on December 24, 2008.

Accession Number
DBSALT000037
Structure
Synonyms
Degarelix (as acetate) / Degarelix acetate / FE-200486 acetate hydrate / FE200486 acetate hydrate