Tapentadol hydrochlorideProduct ingredient for Tapentadol

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.^2,3

Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.⁶ Used in the management of pain, tapentadol is typically reserved for patients who have limited alternative treatment options.