Midodrine hydrochlorideProduct ingredient for Midodrine
- Name
- Midodrine hydrochloride
- Drug Entry
- Midodrine
An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
- Accession Number
- DBSALT000250
- Structure
Structure for Midodrine hydrochloride (DBSALT000250)
- Synonyms
- Midodrine HCl / Midodrine hydrochloride
- UNII
- 59JV96YTXV
- CAS Number
- 43218-56-0
- Weight
- Average: 290.743
Monoisotopic: 290.103334813 - Chemical Formula
- C12H19ClN2O4
- InChI Key
- MGCQZNBCJBRZDT-UHFFFAOYSA-N
- InChI
- InChI=1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H
- IUPAC Name
- 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide hydrochloride
- SMILES
- Cl.COC1=CC(C(O)CNC(=O)CN)=C(OC)C=C1
- External Links
- PubChem Compound
- 18340
- ChemSpider
- 17320
- ChEBI
- 31847
- ChEMBL
- CHEMBL1200461
- Wikipedia
- Midodrine
- Predicted Properties
Property Value Source Water Solubility 4.45 mg/mL ALOGPS logP -0.49 ALOGPS logP -0.95 Chemaxon logS -1.8 ALOGPS pKa (Strongest Acidic) 13.77 Chemaxon pKa (Strongest Basic) 8.14 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 93.81 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 66.22 m3·mol-1 Chemaxon Polarizability 26.57 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon