Mepivacaine hydrochlorideProduct ingredient for Mepivacaine
- Name
- Mepivacaine hydrochloride
- Drug Entry
- Mepivacaine
A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
- Accession Number
- DBSALT000478
- Structure
Structure for Mepivacaine hydrochloride (DBSALT000478)
- Synonyms
- Mepivacaine HCl / Mepivacaine hydrochloride
- UNII
- 4VFX2L7EM5
- CAS Number
- 1722-62-9
- Weight
- Average: 282.809
Monoisotopic: 282.149891075 - Chemical Formula
- C15H23ClN2O
- InChI Key
- RETIMRUQNCDCQB-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H
- IUPAC Name
- N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide hydrochloride
- SMILES
- Cl.CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C
- External Links
- PubChem Compound
- 66070
- ChemSpider
- 59460
- ChEBI
- 6760
- ChEMBL
- CHEMBL1200440
- Wikipedia
- Mepivacaine
- Predicted Properties
Property Value Source Water Solubility 0.621 mg/mL ALOGPS logP 2.16 ALOGPS logP 3.19 Chemaxon logS -2.6 ALOGPS pKa (Strongest Acidic) 13.62 Chemaxon pKa (Strongest Basic) 7.25 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 32.34 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 76.32 m3·mol-1 Chemaxon Polarizability 28.63 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon