Triprolidine hydrochlorideProduct ingredient for Triprolidine

Show full entry for Triprolidine
Name
Triprolidine hydrochloride
Drug Entry
Triprolidine

First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.

See full entry for Triprolidine
Accession Number
DBSALT000623
Structure
Similar Structures
Synonyms
Anhydrous triprolidine hydrochloride / Triprolidine HCl / Triprolidine hydrochloride (anhydrous)
UNII
NG7A104R3J
CAS Number
550-70-9
Weight
Average: 314.852
Monoisotopic: 314.154976453
Chemical Formula
C19H23ClN2
InChI Key
WYUYEJNGHIOFOC-NWBUNABESA-N
InChI
InChI=1S/C19H22N2.ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;/h2-3,6-12H,4-5,13-15H2,1H3;1H/b18-11+;
IUPAC Name
2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine hydrochloride
SMILES
Cl.[H]\C(CN1CCCC1)=C(\C1=CC=C(C)C=C1)C1=CC=CC=N1
PubChem Compound
5702129
ChemSpider
4642507
ChEBI
84119
ChEMBL
CHEMBL1200450
Wikipedia
Triprolidine
Predicted Properties
PropertyValueSource
Water Solubility0.0537 mg/mLALOGPS
logP4.14ALOGPS
logP4.05Chemaxon
logS-3.7ALOGPS
pKa (Strongest Basic)8.64Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area16.13 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity98.53 m3·mol-1Chemaxon
Polarizability32.63 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon