Phenelzine sulfateProduct ingredient for Phenelzine
- Name
- Phenelzine sulfate
- Drug Entry
- Phenelzine
Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder.3 It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
- Accession Number
- DBSALT000954
- Structure
- Synonyms
- Phenelzine acid sulfate / Phenelzine sulphate
- UNII
- 2681D7P965
- CAS Number
- 156-51-4
- Weight
- Average: 234.27
Monoisotopic: 234.067428113 - Chemical Formula
- C8H14N2O4S
- InChI Key
- RXBKMJIPNDOHFR-UHFFFAOYSA-N
- InChI
- InChI=1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)
- IUPAC Name
- (2-phenylethyl)hydrazine; sulfuric acid
- SMILES
- OS(O)(=O)=O.NNCCC1=CC=CC=C1
- External Links
- KEGG Compound
- C07431
- ChemSpider
- 55051
- ChEBI
- 8061
- ChEMBL
- CHEMBL1200895
- Wikipedia
- Phenelzine
- Predicted Properties
Property Value Source Water Solubility 11.1 mg/mL ALOGPS logP 1.2 ALOGPS logP 1.2 Chemaxon logS -1.1 ALOGPS pKa (Strongest Basic) 5.55 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 38.05 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 54.26 m3·mol-1 Chemaxon Polarizability 15.79 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon