Phenelzine sulfateProduct ingredient for Phenelzine

Name
Phenelzine sulfate
Drug Entry
Phenelzine

Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder.3 It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.

Accession Number
DBSALT000954
Structure
Synonyms
Phenelzine acid sulfate / Phenelzine sulphate
UNII
2681D7P965
CAS Number
156-51-4
Weight
Average: 234.27
Monoisotopic: 234.067428113
Chemical Formula
C8H14N2O4S
InChI Key
RXBKMJIPNDOHFR-UHFFFAOYSA-N
InChI
InChI=1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)
IUPAC Name
(2-phenylethyl)hydrazine; sulfuric acid
SMILES
OS(O)(=O)=O.NNCCC1=CC=CC=C1
KEGG Compound
C07431
ChemSpider
55051
ChEBI
8061
ChEMBL
CHEMBL1200895
Wikipedia
Phenelzine
Predicted Properties
PropertyValueSource
Water Solubility11.1 mg/mLALOGPS
logP1.2ALOGPS
logP1.2Chemaxon
logS-1.1ALOGPS
pKa (Strongest Basic)5.55Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area38.05 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity54.26 m3·mol-1Chemaxon
Polarizability15.79 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon