Tamsulosin hydrochlorideProduct ingredient for Tamsulosin

Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.^Label It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.^Label Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor muscles in the bladder, allowing for better urinary flow.^Label Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of blood vessels, resulting in hypotension.⁵

Tamsulosin was first approved by the FDA on April 15, 1997.⁶