Sevelamer hydrochlorideProduct ingredient for Sevelamer

Show full entry for Sevelamer
Name
Sevelamer hydrochloride
Drug Entry
Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.

See full entry for Sevelamer
Accession Number
DBSALT001005
Structure
Similar Structures
Synonyms
Sevelamer HCl / Sevelamer hydrochloride
External IDs
GT-16-026A / GT16-026A
UNII
GLS2PGI8QG
CAS Number
152751-57-0
Weight
Average: 186.08
Monoisotopic: 185.0374194
Chemical Formula
C6H13Cl2NO
InChI Key
KHNXRSIBRKBJDI-UHFFFAOYSA-N
InChI
InChI=1S/C3H5ClO.C3H7N.ClH/c4-1-3-2-5-3;1-2-3-4;/h3H,1-2H2;2H,1,3-4H2;1H
IUPAC Name
2-(chloromethyl)oxirane prop-2-en-1-amine hydrochloride
SMILES
Cl.NCC=C.ClCC1CO1
ChemSpider
140062
ChEBI
32127
Wikipedia
Sevelamer
Predicted Properties
PropertyValueSource
Water Solubility71.8 mg/mLALOGPS
logP0.35ALOGPS
logP0.68Chemaxon
logS-0.11ALOGPS
pKa (Strongest Basic)-4.2Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count1Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area12.53 Å2Chemaxon
Rotatable Bond Count2Chemaxon
Refractivity20.06 m3·mol-1Chemaxon
Polarizability8.38 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon