Dexmedetomidine hydrochlorideProduct ingredient for Dexmedetomidine
- Name
- Dexmedetomidine hydrochloride
- Drug Entry
- Dexmedetomidine
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Accession Number
- DBSALT001013
- Structure
- Synonyms
- Dexmedetomidine HCl
- UNII
- 1018WH7F9I
- CAS Number
- 145108-58-3
- Weight
- Average: 236.74
Monoisotopic: 236.1080263 - Chemical Formula
- C13H17ClN2
- InChI Key
- VPNGEIHDPSLNMU-MERQFXBCSA-N
- InChI
- InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1
- IUPAC Name
- 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole hydrochloride
- SMILES
- Cl.C[C@H](C1=CNC=N1)C1=C(C)C(C)=CC=C1
- External Links
- ChemSpider
- 5293298
- ChEBI
- 31472
- ChEMBL
- CHEMBL2106195
- Wikipedia
- Dexmedetomidine
- Predicted Properties
Property Value Source Water Solubility 0.174 mg/mL ALOGPS logP 3.28 ALOGPS logP 3.39 Chemaxon logS -3.1 ALOGPS pKa (Strongest Acidic) 14.09 Chemaxon pKa (Strongest Basic) 6.54 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 28.68 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 62.98 m3·mol-1 Chemaxon Polarizability 23.32 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon