Levallorphan tartrateProduct ingredient for Levallorphan
- Name
- Levallorphan tartrate
- Drug Entry
- Levallorphan
An opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties. It should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants. (From Martindale, The Extra Pharmacopoeia, 30th ed, p683)
- Accession Number
- DBSALT001040
- Structure
Structure for Levallorphan tartrate (DBSALT001040)
- Synonyms
- Not Available
- UNII
- U0VSF7HTN0
- CAS Number
- 71-82-9
- Weight
- Average: 433.501
Monoisotopic: 433.210052342 - Chemical Formula
- C23H31NO7
- InChI Key
- FWMLYVACGDQRFU-ZTMWJVNESA-N
- InChI
- InChI=1S/C19H25NO.C4H6O6/c1-2-10-20-11-9-19-8-4-3-5-16(19)18(20)12-14-6-7-15(21)13-17(14)19;5-1(3(7)8)2(6)4(9)10/h2,6-7,13,16,18,21H,1,3-5,8-12H2;1-2,5-6H,(H,7,8)(H,9,10)/t16-,18+,19+;1-,2-/m01/s1
- IUPAC Name
- (1R,9R,10R)-17-(prop-2-en-1-yl)-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-trien-4-ol; (2R,3R)-2,3-dihydroxybutanedioic acid
- SMILES
- O[C@H]([C@@H](O)C(O)=O)C(O)=O.OC1=CC2=C(C[C@@H]3[C@@H]4CCCC[C@]24CCN3CC=C)C=C1
- External Links
- ChemSpider
- 21171579
- Wikipedia
- Levallorphan
- Predicted Properties
Property Value Source Water Solubility 0.0252 mg/mL ALOGPS logP 3.91 ALOGPS logP 3.76 Chemaxon logS -4 ALOGPS pKa (Strongest Acidic) 10.36 Chemaxon pKa (Strongest Basic) 9.41 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 23.47 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 87.24 m3·mol-1 Chemaxon Polarizability 32.87 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon