Darifenacin hydrobromideProduct ingredient for Darifenacin

Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence.

Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. This block reduces the urgency to urinate and so it should not be used in people with urinary retention.

It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.