Indoramin hydrochlorideProduct ingredient for Indoramin
- Name
- Indoramin hydrochloride
- Drug Entry
- Indoramin
Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
- Accession Number
- DBSALT001077
- Structure
- Synonyms
- Indoramin HCl
- UNII
- DQ0Z3K8W92
- CAS Number
- 38821-52-2
- Weight
- Average: 383.92
Monoisotopic: 383.1764402 - Chemical Formula
- C22H26ClN3O
- InChI Key
- AFJSFHAKSSWOKG-UHFFFAOYSA-N
- InChI
- InChI=1S/C22H25N3O.ClH/c26-22(17-6-2-1-3-7-17)24-19-11-14-25(15-12-19)13-10-18-16-23-21-9-5-4-8-20(18)21;/h1-9,16,19,23H,10-15H2,(H,24,26);1H
- IUPAC Name
- N-{1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl}benzamide hydrochloride
- SMILES
- Cl.O=C(NC1CCN(CCC2=CNC3=C2C=CC=C3)CC1)C1=CC=CC=C1
- External Links
- ChemSpider
- 34932
- ChEMBL
- CHEMBL2104941
- Predicted Properties
Property Value Source Water Solubility 0.00863 mg/mL ALOGPS logP 3.4 ALOGPS logP 3.19 Chemaxon logS -4.6 ALOGPS pKa (Strongest Acidic) 15.09 Chemaxon pKa (Strongest Basic) 9 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 48.13 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 105.94 m3·mol-1 Chemaxon Polarizability 40.68 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon