Eperisone hydrochlorideProduct ingredient for Eperisone

Name
Eperisone hydrochloride
Drug Entry
Eperisone

Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. It is not approved for use in the United States, but is available in other countries like India, South Korea, and Bangladesh.

Accession Number
DBSALT001099
Structure
Thumb
Synonyms
Eperisone HCl
UNII
U38O8U7P6X
CAS Number
56839-43-1
Weight
Average: 295.85
Monoisotopic: 295.1702922
Chemical Formula
C17H26ClNO
InChI Key
GTAXGNCCEYZRII-UHFFFAOYSA-N
InChI
InChI=1S/C17H25NO.ClH/c1-3-15-7-9-16(10-8-15)17(19)14(2)13-18-11-5-4-6-12-18;/h7-10,14H,3-6,11-13H2,1-2H3;1H
IUPAC Name
1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one hydrochloride
SMILES
Cl.CCC1=CC=C(C=C1)C(=O)C(C)CN1CCCCC1
ChemSpider
110271
ChEBI
31540
ChEMBL
CHEMBL2360601
Predicted Properties
PropertyValueSource
Water Solubility0.0617 mg/mLALOGPS
logP4.27ALOGPS
logP4.01ChemAxon
logS-3.6ALOGPS
pKa (Strongest Acidic)16.34ChemAxon
pKa (Strongest Basic)8.77ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area20.31 Å2ChemAxon
Rotatable Bond Count5ChemAxon
Refractivity80.95 m3·mol-1ChemAxon
Polarizability31.74 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon