Tocainide hydrochlorideProduct ingredient for Tocainide
- Name
- Tocainide hydrochloride
- Drug Entry
- Tocainide
An antiarrhythmic agent which exerts a potential- and frequency-dependent block of sodium channels.
- Accession Number
- DBSALT001138
- Structure
- Synonyms
- Tocainide HCl
- UNII
- 2K7I38CKN5
- CAS Number
- 71395-14-7
- Weight
- Average: 228.72
Monoisotopic: 228.1029409 - Chemical Formula
- C11H17ClN2O
- InChI Key
- AMZACPWEJDQXGW-UHFFFAOYSA-N
- InChI
- InChI=1S/C11H16N2O.ClH/c1-7-5-4-6-8(2)10(7)13-11(14)9(3)12;/h4-6,9H,12H2,1-3H3,(H,13,14);1H
- IUPAC Name
- 2-amino-N-(2,6-dimethylphenyl)propanimidic acid hydrochloride
- SMILES
- Cl.CC(N)C(O)=NC1=C(C)C=CC=C1C
- External Links
- ChemSpider
- 97254
- ChEMBL
- CHEMBL1200773
- Wikipedia
- Tocainide
- Predicted Properties
Property Value Source Water Solubility 0.47 mg/mL ALOGPS logP 1.4 ALOGPS logP 0.35 Chemaxon logS -2.6 ALOGPS pKa (Strongest Acidic) 3.73 Chemaxon pKa (Strongest Basic) 9.56 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 58.61 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 59.61 m3·mol-1 Chemaxon Polarizability 21.8 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon