Ciclopirox olamineProduct ingredient for Ciclopirox

Show full entry for Ciclopirox
Name
Ciclopirox olamine
Drug Entry
Ciclopirox

Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.

See full entry for Ciclopirox
Accession Number
DBSALT001147
Structure
Similar Structures
Synonyms
Not Available
External IDs
HOE 296 / HOE-296
UNII
50MD4SB4AP
CAS Number
41621-49-2
Weight
Average: 268.357
Monoisotopic: 268.178692641
Chemical Formula
C14H24N2O3
InChI Key
MBRHNTMUYWQHMR-UHFFFAOYSA-N
InChI
InChI=1S/C12H17NO2.C2H7NO/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10;3-1-2-4/h7-8,10,15H,2-6H2,1H3;4H,1-3H2
IUPAC Name
2-aminoethan-1-ol; 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one
SMILES
NCCO.CC1=CC(=O)N(O)C(=C1)C1CCCCC1
ChemSpider
35605
ChEMBL
CHEMBL242580
Wikipedia
Ciclopirox
Predicted Properties
PropertyValueSource
Water Solubility1.41 mg/mLALOGPS
logP2.15ALOGPS
logP2.22Chemaxon
logS-2.2ALOGPS
pKa (Strongest Acidic)6.84Chemaxon
pKa (Strongest Basic)-6.2Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area40.54 Å2Chemaxon
Rotatable Bond Count2Chemaxon
Refractivity60.91 m3·mol-1Chemaxon
Polarizability23.13 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon