Cyclizine lactateProduct ingredient for Cyclizine
- Name
- Cyclizine lactate
- Drug Entry
- Cyclizine
A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)
- Accession Number
- DBSALT001182
- Structure
Structure for Cyclizine lactate (DBSALT001182)
- Synonyms
- Not Available
- UNII
- 861R00J986
- CAS Number
- 5897-19-8
- Weight
- Average: 356.466
Monoisotopic: 356.20999277 - Chemical Formula
- C21H28N2O3
- InChI Key
- JOROEVAWQLGPFQ-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H22N2.C3H6O3/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-2(4)3(5)6/h2-11,18H,12-15H2,1H3;2,4H,1H3,(H,5,6)
- IUPAC Name
- 1-(diphenylmethyl)-4-methylpiperazine; 2-hydroxypropanoic acid
- SMILES
- CC(O)C(O)=O.CN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1
- External Links
- ChemSpider
- 64553
- ChEMBL
- CHEMBL1200497
- Wikipedia
- Cyclizine
- Predicted Properties
Property Value Source Water Solubility 0.0752 mg/mL ALOGPS logP 3.55 ALOGPS logP 3.55 Chemaxon logS -3.6 ALOGPS pKa (Strongest Basic) 8.2 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 6.48 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 84.93 m3·mol-1 Chemaxon Polarizability 31.52 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon