Carvedilol phosphateProduct ingredient for Carvedilol

Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.^5,6 It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.^5,6 The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 drugs have a decreased incidence of adverse effects compared to high dose monotherapy in the treatment of moderate hypertension.⁴

Carvedilol was granted FDA approval on 14 September 1995.⁵