Amrinone lactateProduct ingredient for Amrinone
- Name
- Amrinone lactate
- Drug Entry
- Amrinone
Amrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
- Accession Number
- DBSALT001311
- Structure
Structure for Amrinone lactate (DBSALT001311)
- Synonyms
- Inamrinone lactate
- UNII
- I229274Y5B
- CAS Number
- 75898-90-7
- Weight
- Average: 277.28
Monoisotopic: 277.106255975 - Chemical Formula
- C13H15N3O4
- InChI Key
- DOSIONJFGDSKCQ-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H9N3O.C3H6O3/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7;1-2(4)3(5)6/h1-6H,11H2,(H,13,14);2,4H,1H3,(H,5,6)
- IUPAC Name
- 2-hydroxypropanoic acid; 5-amino-1,6-dihydro-[3,4'-bipyridine]-6-one
- SMILES
- CC(O)C(O)=O.NC1=CC(=CNC1=O)C1=CC=NC=C1
- External Links
- ChemSpider
- 2299493
- ChEMBL
- CHEMBL2096642
- Predicted Properties
Property Value Source Water Solubility 5.6 mg/mL ALOGPS logP 0.27 ALOGPS logP -0.57 Chemaxon logS -1.5 ALOGPS pKa (Strongest Acidic) 11.01 Chemaxon pKa (Strongest Basic) 4.87 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 68.01 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 53.89 m3·mol-1 Chemaxon Polarizability 18.93 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon