Toremifene citrateProduct ingredient for Toremifene

Toremifene is a selective estrogen receptor modulator (SERM) and a nonsteroidal antiestrogen used to treat estrogen receptor positive breast cancer.⁶ Like tamoxifen, toremifene is part of the first-generation triphenylethylene derivative chemical class of SERMs.⁷

Toremifene possesses tissue-specific actions: it has estrogenic (agonist) activity on the cardiovascular system and on bone tissue and it has weak estrogenic effects on uterine tissue, however, it also has antiestrogenic (estrogen-antagonist) activity on breast tissue.⁶