Etafedrine hydrochlorideProduct ingredient for Etafedrine

Name
Etafedrine hydrochloride
Drug Entry
Etafedrine

Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin 3 and Dalmacol 10. It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued 7.

Ethylephedrine is be formed by alkylating ephedrine with ethyl iodide. The hydrochloride is be prepared by passing hydrogen chloride through a solution of ethylephedrine in diethyl ether 11.

This belongs to the family of medications called decongestants. It acts by narrowing blood vessels in the nasal passages, helping to relieve nasal congestion 11.

Accession Number
DBSALT001778
Structure
Synonyms
(-)-2-(ethylmethylamino)-1-phenylpropan-1-ol hydrochloride / (-)-ethylephedrine hydrochloride / alpha-(1-(ethylmethylamino)ethyl)benzyl alcohol hydrochloride / Etafedrin hydrochloride / Etafedrine HCl / Nethamine