Saprisartan potassiumProduct ingredient for Saprisartan

Show full entry for Saprisartan
Name
Saprisartan potassium
Drug Entry
Saprisartan

Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism 1.

See full entry for Saprisartan
Accession Number
DBSALT001863
Structure
MOLSDFPDBSMILESInChI
Synonyms
1-((3-bromo-2-(2-(((trifluoro-methyl)sulfonyl)amino)phenyl)-5-benzofuranyl)methyl)-4-cyclopropyl-2-ethyl-1h-imidazole-5-carboxamide potassium / 1-((3-bromo-2-(o-(1,1,1-(trifluoromethanesulfonamido)phenyl)-5-benzofuranyl)methyl)-4-cyclopropyl-2-ethylimidazole-5-carboxamide, monopotassium salt
External IDs
GR-138950C