Mosapride CitrateProduct ingredient for Mosapride
- Name
- Mosapride Citrate
- Drug Entry
- Mosapride
Mosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). Mosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional Dyspepsia, Functional Constipation, and Epigastric Pain Syndrome, among others.
- Accession Number
- DBSALT002047
- Structure
- Synonyms
- Not Available
- UNII
- MF497J489P
- CAS Number
- 112885-42-4
- Weight
- Average: 614.02
Monoisotopic: 613.1838501 - Chemical Formula
- C27H33ClFN3O10
- InChI Key
- HUZTYZBFZKRPFG-UHFFFAOYSA-N
- InChI
- InChI=1S/C21H25ClFN3O3.C6H8O7/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
- IUPAC Name
- 2-hydroxypropane-1,2,3-tricarboxylic acid; 4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzene-1-carboximidic acid
- SMILES
- OC(=O)CC(O)(CC(O)=O)C(O)=O.CCOC1=C(C=C(Cl)C(N)=C1)C(O)=NCC1CN(CC2=CC=C(F)C=C2)CCO1
- External Links
- ChemSpider
- 106779
- ChEMBL
- CHEMBL1733174
- Predicted Properties
Property Value Source Water Solubility 0.0237 mg/mL ALOGPS logP 3.04 ALOGPS logP 3.46 Chemaxon logS -4.2 ALOGPS pKa (Strongest Acidic) 7.9 Chemaxon pKa (Strongest Basic) 6.06 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 80.31 Å2 Chemaxon Rotatable Bond Count 12 Chemaxon Refractivity 112.86 m3·mol-1 Chemaxon Polarizability 43.82 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon