Nicotinamide hydrochlorideProduct ingredient for Nicotinamide
- Name
- Nicotinamide hydrochloride
- Drug Entry
- Nicotinamide
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
- Accession Number
- DBSALT002262
- Structure
Structure for Nicotinamide hydrochloride (DBSALT002262)
- Synonyms
- Niacinamide hydrochloride / Nicotinamide hydrochloride
- UNII
- 4D16EOF1QW
- CAS Number
- 25334-23-0
- Weight
- Average: 158.59
Monoisotopic: 158.0246906 - Chemical Formula
- C6H7ClN2O
- InChI Key
- OBLVPWTUALCMGD-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H6N2O.ClH/c7-6(9)5-2-1-3-8-4-5;/h1-4H,(H2,7,9);1H
- IUPAC Name
- pyridine-3-carboxamide hydrochloride
- SMILES
- Cl.NC(=O)C1=CN=CC=C1
- External Links
- ChemSpider
- 82540
- Predicted Properties
Property Value Source Water Solubility 50.1 mg/mL ALOGPS logP -0.45 ALOGPS logP -0.39 Chemaxon logS -0.39 ALOGPS pKa (Strongest Acidic) 13.39 Chemaxon pKa (Strongest Basic) 3.63 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 55.98 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 32.98 m3·mol-1 Chemaxon Polarizability 11.71 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon