Benzophenone-5Product ingredient for Sulisobenzone
- Name
- Benzophenone-5
- Drug Entry
- Sulisobenzone
Sulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations 14. It works to filter out both UVA and UVB rays, protecting the skin from sun UV damage 8.
The UV-filter substance, sulisobenzone (BP-4) is widely used an ingredient in sunscreens and other personal care products 1, 10. It falls under the drug category of benzophenones. The benzophenones are a group of aromatic ketones that have both pharmaceutical and industrial applications 13. Benzophenones may be found organically in fruits such as grapes 11.
Benzophenones are used as photoinitiators, fragrance enhancers, ultraviolet curing agents, and, occasionally, as flavor ingredients; they are also used in the manufacture of insecticides, agricultural chemicals, and pharmaceuticals and as an additive for plastics, coatings, and adhesives 12.
As a group, benzophenones may be used to delay photodegradation or extend shelf life in toiletries and plastic surface coatings 13.
- Accession Number
- DBSALT002279
- Structure
Structure for Benzophenone-5 (DBSALT002279)
- Synonyms
- Benzophenone 5 / Sodium 2-hydroxy-4-methoxybenzophenone-5-sulphonate / Sodium 5-benzoyl-4-hydroxy-2-methoxybenzenesulphonate / Sodium benzophenone-2-hydroxy-4-methoxy-5-sulfonate / Sodium benzophenone-2-hydroxy-4-methoxy-5-sulphonate / Sulisobenzone sodium
- UNII
- 853Z42ZYAS
- CAS Number
- 6628-37-1
- Weight
- Average: 330.29
Monoisotopic: 330.01740353 - Chemical Formula
- C14H11NaO6S
- InChI Key
- KJCLYACXIWMFCC-UHFFFAOYSA-M
- InChI
- InChI=1S/C14H12O6S.Na/c1-20-12-8-11(15)10(7-13(12)21(17,18)19)14(16)9-5-3-2-4-6-9;/h2-8,15H,1H3,(H,17,18,19);/q;+1/p-1
- IUPAC Name
- sodium 5-benzoyl-4-hydroxy-2-methoxybenzene-1-sulfonate
- SMILES
- [Na+].COC1=CC(O)=C(C=C1S([O-])(=O)=O)C(=O)C1=CC=CC=C1
- External Links
- ChemSpider
- 4957574
- Wikipedia
- Sulisobenzone
- Predicted Properties
Property Value Source Water Solubility 0.229 mg/mL ALOGPS logP 2.33 ALOGPS logP 2.8 Chemaxon logS -3.2 ALOGPS pKa (Strongest Acidic) -2.4 Chemaxon pKa (Strongest Basic) -5 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 103.73 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 74.58 m3·mol-1 Chemaxon Polarizability 28.73 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon