Ketoprofen sodiumProduct ingredient for Ketoprofen

Name
Ketoprofen sodium
Drug Entry
Ketoprofen

Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.

Accession Number
DBSALT002292
Structure
Synonyms
Not Available
UNII
5R10M39KS7
CAS Number
57495-14-4
Weight
Average: 276.267
Monoisotopic: 276.07623856
Chemical Formula
C16H13NaO3
InChI Key
OAPDLBHLMVYMCW-UHFFFAOYSA-M
InChI
InChI=1S/C16H14O3.Na/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12;/h2-11H,1H3,(H,18,19);/q;+1/p-1
IUPAC Name
sodium 2-(3-benzoylphenyl)propanoate
SMILES
[Na+].CC(C([O-])=O)C1=CC=CC(=C1)C(=O)C1=CC=CC=C1
ChemSpider
38660
BindingDB
50224291
ChEMBL
CHEMBL341922
Predicted Properties
PropertyValueSource
Water Solubility0.0165 mg/mLALOGPS
logP3.27ALOGPS
logP3.61Chemaxon
logS-4.2ALOGPS
pKa (Strongest Acidic)3.88Chemaxon
pKa (Strongest Basic)-7.5Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area57.2 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity83.35 m3·mol-1Chemaxon
Polarizability26.48 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon