Fenspiride hydrochlorideProduct ingredient for Fenspiride
- Name
- Fenspiride hydrochloride
- Drug Entry
- Fenspiride
Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. It is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis), as well as for maintenance treatment of asthma.
- Accession Number
- DBSALT002867
- Structure
- Synonyms
- Fenspiride HCl / Fenspiride hydrochloride
- External IDs
- JP 428 / NAT-333 / NDR-5998A
- UNII
- 832NBX878V
- CAS Number
- 5053-08-7
- Weight
- Average: 296.8
Monoisotopic: 296.1291556 - Chemical Formula
- C15H21ClN2O2
- InChI Key
- FIKFLLIUPUVONI-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H20N2O2.ClH/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13;/h1-5H,6-12H2,(H,16,18);1H
- IUPAC Name
- 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
- SMILES
- Cl.O=C1NCC2(CCN(CCC3=CC=CC=C3)CC2)O1
- External Links
- ChemSpider
- 61885
- ChEMBL
- CHEMBL1256849
- Predicted Properties
Property Value Source Water Solubility 2.75 mg/mL ALOGPS logP 1.42 ALOGPS logP 1.6 Chemaxon logS -2 ALOGPS pKa (Strongest Acidic) 13.29 Chemaxon pKa (Strongest Basic) 8.97 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 41.57 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 73.73 m3·mol-1 Chemaxon Polarizability 29.14 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon