Caramiphen hydrochlorideProduct ingredient for Caramiphen

Show full entry for Caramiphen
Name
Caramiphen hydrochloride
Drug Entry
Caramiphen

Caramiphen is a cholinergic antagonist used in Parkinson's disease. Additionally, it is used, in combination with phenylpropanolamine, as a cough suppressant and nasal decongestant for the symptomatic treatment of seasonal respiratory conditions.

See full entry for Caramiphen
Accession Number
DBSALT002875
Structure
Similar Structures
Synonyms
Caramiphen HCl / Caramiphene hydrochloride
UNII
4858SN190E
CAS Number
125-85-9
Weight
Average: 325.88
Monoisotopic: 325.1808568
Chemical Formula
C18H28ClNO2
InChI Key
MUPNXGNOIBYHSG-UHFFFAOYSA-N
InChI
InChI=1S/C18H27NO2.ClH/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16;/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3;1H
IUPAC Name
2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate hydrochloride
SMILES
Cl.CCN(CC)CCOC(=O)C1(CCCC1)C1=CC=CC=C1
ChemSpider
60517
ChEMBL
CHEMBL1598472
Predicted Properties
PropertyValueSource
Water Solubility0.0437 mg/mLALOGPS
logP4.31ALOGPS
logP4.01Chemaxon
logS-3.8ALOGPS
pKa (Strongest Basic)8.96Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area29.54 Å2Chemaxon
Rotatable Bond Count8Chemaxon
Refractivity86.13 m3·mol-1Chemaxon
Polarizability34.2 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon