Pilsicainide hydrochlorideProduct ingredient for Pilsicainide

Name
Pilsicainide hydrochloride
Drug Entry
Pilsicainide

Pilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.

Accession Number
DBSALT002921
Structure
Synonyms
Pilsicainide HCl / Pilsicainide hydrochloride
External IDs
SUN 1165
UNII
03C8I9296V
CAS Number
88069-49-2
Weight
Average: 308.85
Monoisotopic: 308.1655411
Chemical Formula
C17H25ClN2O
InChI Key
NZOSVDHCTCLGEB-UHFFFAOYSA-N
InChI
InChI=1S/C17H24N2O.ClH/c1-13-6-3-7-14(2)16(13)18-15(20)12-17-8-4-10-19(17)11-5-9-17;/h3,6-7H,4-5,8-12H2,1-2H3,(H,18,20);1H
IUPAC Name
N-(2,6-dimethylphenyl)-2-(hexahydro-1H-pyrrolizin-7a-yl)acetamide hydrochloride
SMILES
Cl.CC1=CC=CC(C)=C1NC(=O)CC12CCCN1CCC2
ChemSpider
102779
Predicted Properties
PropertyValueSource
Water Solubility0.389 mg/mLALOGPS
logP2.36ALOGPS
logP3.16Chemaxon
logS-2.8ALOGPS
pKa (Strongest Acidic)14.44Chemaxon
pKa (Strongest Basic)10.46Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area32.34 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity83.77 m3·mol-1Chemaxon
Polarizability31.15 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon