Etilefrine hydrochlorideProduct ingredient for Etilefrine
- Name
- Etilefrine hydrochloride
- Drug Entry
- Etilefrine
Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
- Accession Number
- DBSALT002970
- Structure
Structure for Etilefrine hydrochloride (DBSALT002970)
- Synonyms
- dl-Etilefrin hydrochloride / Etifelmine hydrochloride / Etilefrine HCl / Etilefrine hydrochloride
- UNII
- ZBI6Q5FH3S
- CAS Number
- 943-17-9
- Weight
- Average: 217.69
Monoisotopic: 217.0869565 - Chemical Formula
- C10H16ClNO2
- InChI Key
- KTNROWWHOBZQGK-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H15NO2.ClH/c1-2-11-7-10(13)8-4-3-5-9(12)6-8;/h3-6,10-13H,2,7H2,1H3;1H
- IUPAC Name
- 3-[2-(ethylamino)-1-hydroxyethyl]phenol hydrochloride
- SMILES
- Cl.CCNCC(O)C1=CC=CC(O)=C1
- External Links
- ChemSpider
- 13079
- ChEBI
- 31582
- ChEMBL
- CHEMBL3187408
- Predicted Properties
Property Value Source Water Solubility 13.8 mg/mL ALOGPS logP 0.01 ALOGPS logP 0.23 Chemaxon logS -1.1 ALOGPS pKa (Strongest Acidic) 9.1 Chemaxon pKa (Strongest Basic) 9.73 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 52.49 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 52 m3·mol-1 Chemaxon Polarizability 20.33 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon