Lercanidipine hydrochlorideProduct ingredient for Lercanidipine
- Name
- Lercanidipine hydrochloride
- Drug Entry
- Lercanidipine
Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
- Accession Number
- DBSALT002974
- Structure
Structure for Lercanidipine hydrochloride (DBSALT002974)
- Synonyms
- Lercanidipine HCl / Lercanidipine hydrochloride
- External IDs
- R 75
- UNII
- OA8TFX68PE
- CAS Number
- 132866-11-6
- Weight
- Average: 648.2
Monoisotopic: 647.2762138 - Chemical Formula
- C36H42ClN3O6
- InChI Key
- WMFYOYKPJLRMJI-UHFFFAOYSA-N
- InChI
- InChI=1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H
- IUPAC Name
- 3-{1-[(3,3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
- SMILES
- Cl.COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC(C)(C)CN(C)CCC(C1=CC=CC=C1)C1=CC=CC=C1
- External Links
- ChemSpider
- 138945
- ChEBI
- 31771
- ChEMBL
- CHEMBL2106419
- Predicted Properties
Property Value Source Water Solubility 0.000156 mg/mL ALOGPS logP 6.42 ALOGPS logP 6.41 Chemaxon logS -6.6 ALOGPS pKa (Strongest Acidic) 16.96 Chemaxon pKa (Strongest Basic) 9.36 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 111.01 Å2 Chemaxon Rotatable Bond Count 14 Chemaxon Refractivity 176.85 m3·mol-1 Chemaxon Polarizability 66.15 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon