Antazoline hydrochlorideProduct ingredient for Antazoline
- Name
- Antazoline hydrochloride
- Drug Entry
- Antazoline
Antazoline is a 1st generation antihistamine with anticholinergic activity. It is used to relieve nasal congestion. It is also formulated as eye drops with naphazoline to relieve allergic conjunctivitis.
- Accession Number
- DBSALT003072
- Structure
Structure for Antazoline hydrochloride (DBSALT003072)
- Synonyms
- Antazoline HCl / Antazoline hydrochloride
- External IDs
- 219-719-8
- UNII
- FP8Q8F72JH
- CAS Number
- 2508-72-7
- Weight
- Average: 301.82
Monoisotopic: 301.1345754 - Chemical Formula
- C17H20ClN3
- InChI Key
- SWKDMSRRIBZZAY-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H19N3.ClH/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;/h1-10H,11-14H2,(H,18,19);1H
- IUPAC Name
- N-benzyl-N-[(4,5-dihydro-1H-imidazol-2-yl)methyl]aniline hydrochloride
- SMILES
- Cl.C(N(CC1=CC=CC=C1)C1=CC=CC=C1)C1=NCCN1
- External Links
- ChemSpider
- 16349
- ChEMBL
- CHEMBL1256819
- Predicted Properties
Property Value Source Water Solubility 0.114 mg/mL ALOGPS logP 3.22 ALOGPS logP 2.88 Chemaxon logS -3.4 ALOGPS pKa (Strongest Basic) 9.24 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 27.63 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 82.89 m3·mol-1 Chemaxon Polarizability 30.09 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon