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Somatostatin
go.drugbank.com/drugs/DB09099ApprovedInvestigationalWithdrawnIt is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating … The actions of somatostatin are mediated via signalling pathways of G protein-coupled somatostatin receptors.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: SOMATOSTATIN EUMEDICA 250 MCG IV INFÜZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET, SOMATOSTATIN EUMEDICA 3 MG IV INF. ICIN LIYOFILIZE TOZ ICEREN FLAKONDuloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more. … [label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: DU-TWO ® 60 MG, TQ INMOX 60 MG CAPSULASFluticasone furoate
go.drugbank.com/drugs/DB08906ApprovedInvestigationalFluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label] . Fluticasone furoate was first approved in 2007 .
Mixtures: RELVAR ELLIPTA 100/25 MCG KULLANIMA HAZIR INHALASYON TOZU ,3 X 30, REVINTY ELLIPTA 100/25 MCG KULLANIMA HAZIR INHALASYON TOZU, 30 D0ZCategories: Agents to Treat Airway Disease, Cytochrome P-450 SubstratesFelodipine
go.drugbank.com/drugs/DB01023ApprovedFelodipine is used to treat mild to moderate essential hypertension. … In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent
Synonyms: 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylateMixtures: DELMUNO 5/5 MG, DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADETPantoprazole
go.drugbank.com/drugs/DB00213ApprovedInvestigationalPantoprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme … As the binding of pantoprazole to the (H+, K+)-ATPase enzyme is irreversible and new enzyme needs to be expressed in order to resume acid secretion, pantoprazole's duration of antisecretory effect persists
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: PANTO 40 MG IV ENJEKSIYONLUK LIYOFILIZE TOZ ICEREN FLAKON, 10 ADET, PANTOZOL 40 MG IV ENJEKSIYONLUK LIYOFILIZE TOZ IÇEREN FLAKON, 10 ADETDelafloxacin
go.drugbank.com/drugs/DB11943ApprovedInvestigationalDelafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections, and Community Acquired Pneumonia, a...
Categories: Cytochrome P-450 CYP2C9 Inducers, Cytochrome P-450 CYP3A InducersProducts: Quofenix 300 mg İnfüzyonluk Çözelti Hazırlamada Kullanılacak Konsantre İçin Toz, 10 ADET, Quofenix 450 mg Tablet, 10 ADETColistimethate
go.drugbank.com/drugs/DB01111ApprovedInvestigationalVet approvedColistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. … Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
Products: COLIJECT ® 150 MG / VIAL, COLIMYCIN 150 MG IM/IV ENJEKSİYON VE INHALASYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADETErgoloid mesylate
go.drugbank.com/drugs/DB01049Approved[A32914] The mixture of ergoloid mesylate was first developed by Novartis and FDA approved on November 5, 1953, but this specific formulation is now discontinued. … [T90] The derivatives of this fungus are identified to be about 350 different substances from which the components of the ergoloid mesylate mixture are composed of the dihydrogenated ergot alkaloid derivatives
Synonyms: co-dergocrine mesilate, co-dergocrine mesylateMixtures: TOTERJİN DAMLA, 50 CCLumiracoxib
go.drugbank.com/drugs/DB01283ApprovedWithdrawnOn August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acidDrospirenone
go.drugbank.com/drugs/DB01395ApprovedInvestigational[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and premenstrual dysphoric disorder (PMDD). … Drospirenone has been the subject of widespread safety concern due to the possibility of an increased risk of venous thromboembolism associated with its use.
Mixtures: Lo-Zumandimine, VERONIQ ® 3 MG / 30 MCGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates