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Displaying results 1011 - 1020 of 10000 in total
  1. Drug

    Tacrine

    go.drugbank.com/drugs/DB00382
    ApprovedWithdrawn

    A centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: 5-amino-6,7,8,9-tetrahydroacridine, 1,2,3,4-tetrahydro-9-acridinamine
  2. Drug

    Crozbaciclib

    go.drugbank.com/drugs/DB18081
    Experimental

    Synonyms: 2-PYRIMIDINAMINE, 5-FLUORO-4-(7'-FLUORO-2'-METHYLSPIRO(CYCLOPENTANE-1,3'-(3H)INDOL)-5'-YL)-N-(5-(1-METHYL-4-PIPERIDINYL)-2-PYRIDINYL)-, 5-fluoro-4-(7'-fluoro-2'-methylspiro[cyclopentane-1,3'- indol]-5'-yl)-N-[5-(1-methylpiperidin-4-yl)pyridin-2- yl]pyrimidin-2-amine
  3. Drug

    (4S)-5-[[(1S)-1-Carboxy-2-cyclohexylethyl]amino]-4-[[(2S)-2-[[(3R)-4-cyclohexyl-2-oxo-3-(phenylmethoxycarbonylamino)butanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoic acid

    go.drugbank.com/drugs/DB01984
    Experimental

    Synonyms: (4S)-5-[[(1S)-1-Carboxy-2-cyclohexylethyl]amino]-4-[[(2S)-2-[[(3R)-4-cyclohexyl-2-oxo-3-(phenylmethoxycarbonylamino)butanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoic acid
  4. Drug

    1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z)

    go.drugbank.com/drugs/DB08742
    Experimental

    Synonyms: 1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z)
  5. Drug

    D-arginine

    go.drugbank.com/drugs/DB04027
    Experimental

    A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active).

    Synonyms: D-2-Amino-5-guanidinovaleric acid, (R)-2-amino-5-guanidinopentanoic acid
  6. Drug

    Eteplirsen

    go.drugbank.com/drugs/DB06014
    ApprovedInvestigational

    Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. … It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA.

    Synonyms: (P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G),5'-(P-(4-((2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)carbonyl, )-1-piperazinyl)-N,N-dimethylphosphonamidate) RNACategories: Heterocyclic Compounds, 1-Ring, Nucleic Acids, Nucleotides, and Nucleosides
  7. Drug

    Enpatoran

    go.drugbank.com/drugs/DB16501
    Investigational

    Additionally, M5049 was studied for COVID-19 pneumonia in a completed trial with results (NCT04448756) and is currently being recruited for a trial involving participants with dermatomyositis and polymyositis … It was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327).

    Categories: Experimental Unapproved Treatments for COVID-19Synonyms: 5-((3R,5S)-3-AMINO-5-TRIFLUOROMETHYLPIPERIDIN-1-YL)QUINOLINE-8-CARBONITRILE
  8. Drug

    Pyridoxal

    go.drugbank.com/drugs/DB00147
    ExperimentalNutraceutical

    The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic

    Categories: Heterocyclic Compounds, 1-Ring, Vitamin B ComplexSynonyms: 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde
  9. Drug

    Bezuclastinib

    go.drugbank.com/drugs/DB18041
    Investigational

    Synonyms: 3,4-dimethyl-n-(2-phenyl-1h-pyrrolo(2,3-b)pyridin-5-yl)-1h-pyrazole-5-carboxamide, 3,4-dimethyl-N-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-5- carboxamide
  10. Drug

    [(5R)-5-(2,3-dibromo-5-ethoxy-4-hydroxybenzyl)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid

    go.drugbank.com/drugs/DB06998
    Experimental

    Synonyms: [(5R)-5-(2,3-dibromo-5-ethoxy-4-hydroxybenzyl)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid